Mouse Anti-Human SOD2 Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | P04179 |
| Gene Id | 6648 |
| Gene Symbols | SOD2 |
| Protein Name / Synonyms | SOD2 |
| Clonality | Monoclonal |
| Preparation | Purified His-tagged SOD protein(Fragment) was used to produced this monoclonal antibody. |
| Concentration (lot specific) | 0.340 mg/ml |
| Recommended Applications | IHC-P, Western Blotting |
| Research Area | Angiogenesis, Cardiovascular Disease, Oxidative Stress |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Specificity
Other Names
SOD2; Superoxide dismutase [Mn], mitochondrial
NCBI Accession #
NP_000627.2;NP_001019636.1;NP_001019637.1
Format
Type
Purified Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
24722
Recommended Dilutions
IHC: 1:10-50; WB: 1:2000
 | Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with SOD2 Monoclonal Antibody (Cat# 102-10501), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Western blot analysis of anti-SOD2 Monoclonal Antibody (Cat# 102-10501) by SOD2-GST fusion protein (GST MW=26 kD. SOD2-GST fusion protein (arrow) was detected using the purified Mab. (1:2000) |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.