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Anti-SPPL2a (N-term) Antibody
Catalog #: 102-27007
Rabbit Anti-SPPL2a (N-term) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q8TCT8 |
| Gene Id | 84888 |
| Gene Symbols | SPP2A |
| Protein Name / Synonyms | Signal peptide peptidase-like 2A, SPP-like 2A, SPPL2a, 3423-, Intramembrane protease 3, IMP-3, Presenilin-like protein 2, SPPL2A, IMP3, PSL2 |
| Clonality | Polyclonal |
| Clone | RB2267 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
By searching sequence databases for homologs of Dictyostelium discoideum Impas, which shares homology with presenilin, followed by PCR of lymphocyte and hippocampus cDNA libraries, Grigorenko et al. (2002) cloned SPPL2a. This protein, which may act as an intramembrane protease, contains an N-terminal protease-associated (PA) domain, several transmembrane regions, a hydrophilic loop, conservative sequences around the first and second aspartate residues, and an invariant PAL motif near the C terminus.
Other Information
NCBI Accession #
NP_116191.2
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Calculated Molecular Weight (Da)
58143
Antigen Source
Human
Images
WB (1:1000)
The anti-SPPL2a Pab (Cat. #102-27007) is used in Western blot to detect SPPL2a in Jurkat cell lysate.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.