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Anti-SPRY2 (N-term) Antibody
Catalog #: 102-13402
Rabbit Anti-SPRY2 (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | O43597 |
| Gene Id | 10253 |
| Gene Symbols | SPRY2 |
| Protein Name / Synonyms | SPRY2 (N-term) |
| Clonality | Polyclonal |
| Preparation | This SPRY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-35 amino acids from the N-terminal region of human SPRY2. |
| Concentration (lot specific) | 0.400 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Angiogenesis |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq].
Specificity
Predicted Reactivity
Monkey
Other Names
SPRY2; Protein sprouty homolog 2
NCBI Accession #
NP_005833.1
Other Accession #
Q2PFN5; NP_005833.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
34688
Recommended Dilutions
WB: 1:1000
 | SPRY2 Antibody (N-term) (Cat# 102-13402) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SPRY2 antibody detected the SPRY2 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.