Anti-SRRT (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9BXP5\|Q99MR6\|A4IFB1\|NP_001122325.1\|NP_001122324.1
Gene Id	51593
Gene Symbols	SRRT
Protein Name / Synonyms	Serrate RNA effector molecule homolog, Arsenite-resistance protein 2, SRRT, ARS2, ASR2
Clonality	Polyclonal
Clone	RB37036
Isotype	Kappa, Rabbit
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

SRRT acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and RNASEN, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.

Other Information

NCBI Accession #

NP_001122324.1;NP_001122325.1;NP_001122326.1;NP_056992.4

Antigen Type

Synthetic Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

100666

Antigen Source

Human

Images

WB (1:1000)

SRRT Antibody (N-term) (Cat. #102-22657) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SRRT antibody detected the SRRT protein (arrow).

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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