Rabbit Anti-Human SSB (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P05455 |
| Gene Id | 6741 |
| Gene Symbols | SSB |
| Protein Name / Synonyms | SSB (C-term) |
| Clonality | Polyclonal |
| Preparation | This SSB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-397 amino acids from the C-terminal region of human SSB. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | IHC-P, Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
SSB is involved in diverse aspects of RNA metabolism, including binding and protecting 3-prime UUU(OH) elements of newly RNA polymerase III -transcribed RNA, processing 5-prime and 3-prime ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. This protein was originally defined by its reactivity with autoantibodies from patients with Sjogren syndrome and systemic lupus erythematosus.
Specificity
Predicted Reactivity
Rabbit
Other Names
SSB; Lupus La protein; La autoantigen; La ribonucleoprotein; Sjoegren syndrome type B antigen
NCBI Accession #
NP_003133.1
Other Accession #
Q04504
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
46837
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of SSB Antibody (C-term) (Cat# 102-15148) in K562, Hela, 293 cell line lysates (35ug/lane). SSB (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SSB Antibody (C-term) (Cat# 102-15148), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.