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Anti-ST14 (C-term) Antibody

Catalog #: 102-16701

Rabbit Anti-Mouse ST14 (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesMouse
Host SpeciesRabbit
Accession Number
Q9Y5Y6
Gene Id
6768
Gene Symbols
ST14
Protein Name / Synonyms
ST14 (C-term)
ClonalityPolyclonal
PreparationThis ST14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 826-855 amino acids from the C-terminal region of human ST14.
Concentration (lot specific)
0.400 mg/ml
Recommended ApplicationsWestern Blotting, IHC-P
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.

Specificity

Other Names
ST14; PRSS14; SNC19; TADG15; Suppressor of tumorigenicity 14 protein; Matriptase; Membrane-type serine protease 1; Prostamin; Serine protease 14; Serine protease TADG-15; Tumor-associated differentially-expressed gene 15 protein
NCBI Accession #
NP_068813.1
Other Accession #
NP_068813

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
94770
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
ST14 Antibody (C-term R841) (Cat# 102-16701) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the ST14 antibody detected the ST14 protein (arrow).
ST14 Antibody (C-term) (Cat# 102-16701)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ST14 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.