Anti-STAT1 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P42224
Gene Id	6772
Gene Symbols	STAT1
Protein Name / Synonyms	STAT1 (C-term)
Clonality	Polyclonal
Preparation	This STAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 717-745 amino acids from the C-terminal region of human STAT1.
Concentration (lot specific)	0.470 mg/ml
Recommended Applications	FC, Western Blotting
Research Area	Angiogenesis, Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq].

Specificity

Other Names

STAT1; Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3 components p91/p84

NCBI Accession #

NP_009330.1;NP_644671.1

Other Accession #

NP_009330.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

87335

Recommended Dilutions

WB: 1:1000

STAT1 Antibody (C-term) (Cat# 102-14440) western blot analysis in Hela,Jurkat cell line lysates (35ug/lane).This demonstrates the STAT1 antibody detected the STAT1 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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