Anti-STAT2 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P52630
Gene Id	6773
Gene Symbols	STAT2
Protein Name / Synonyms	STAT2 (N-term)
Clonality	Polyclonal
Preparation	This STAT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the N-terminal region of human STAT2.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Specificity

Predicted Reactivity

Pig

Other Names

STAT2; Signal transducer and activator of transcription 2; p113

NCBI Accession #

NP_005410.1;NP_938146.1

Other Accession #

O02799; NP_005410.1; NP_938146.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

97916

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	STAT2 Antibody (N-term) (Cat# 102-12137) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the STAT2 antibody detected the STAT2 protein (arrow).
	STAT2 Antibody (N-term) (Cat# 102-12137)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of STAT2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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