3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-STAT3 Antibody
Catalog #: 102-10514
Mouse Anti-Human STAT3 Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Accession Number | P40763 |
| Gene Id | 6774 |
| Gene Symbols | STAT3 |
| Protein Name / Synonyms | STAT3 |
| Clonality | Monoclonal |
| Preparation | This STAT3 antibody is generated from a mouse immunized with a recombinant protein from human. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Angiogenesis, Cancer, Inflammation, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)- responsive elements identified in the promoters of various acute- phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity).
Specificity
Predicted Reactivity
Mouse, Rat, Pig
Other Names
Signal transducer and activator of transcription 3, Acute-phase response factor, STAT3, APRF
Other Accession #
P52631; Q19S50; P42227
Format
Type
Purified Mouse Monoclonal Antibody (Mab)
Calculated Molecular Weight (Da)
88068
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of lysates from CEM, Hela cell line (from left to right), using Stat3 Antibody(Cat# 102-10514). 102-10514 was diluted at 1:1000 at each lane. A goat anti-mouse IgG H&L(HRP) at 1:3000 dilution was used as the secondary antibody. Lysates at 35ug per lane. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.