Rabbit Anti-Human STX1A (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q16623 |
| Gene Id | 6804 |
| Gene Symbols | STX1A |
| Protein Name / Synonyms | STX1A (N-term) |
| Clonality | Polyclonal |
| Preparation | This STX1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human STX1A. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a member of the syntaxin superfamily. Syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane. Syntaxins possess a single C-terminal transmembrane domain, a SNARE [Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein REceptor] domain (known as H3), and an N-terminal regulatory domain (Habc). Syntaxins bind synaptotagmin in a calcium-dependent fashion and interact with voltage dependent calcium and potassium channels via the C-terminal H3 domain. This gene product is a key molecule in ion channel regulation and synaptic exocytosis.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
STX1A; STX1; Syntaxin-1A; Neuron-specific antigen HPC-1
NCBI Accession #
NP_001159375.1;NP_004594.1
Other Accession #
P32851; O35526
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
33023
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | Western blot analysis of STX1A Antibody (N-term) (Cat# 102-18403) in 293 cell line lysates (35ug/lane). STX1A (arrow) was detected using the purified Pab. |
 | STX1A Antibody (N-term) (Cat# 102-18403) IHC analysis in formalin fixed and paraffin embedded skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the STX1A Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | STX1A Antibody (N-term) (Cat# 102-18403) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.