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Anti-SUV39H2 (C-term) Antibody
Catalog #: 102-14145
Rabbit Anti-Human SUV39H2 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9H5I1 |
| Gene Id | 79723 |
| Gene Symbols | SUV39H2 |
| Protein Name / Synonyms | SUV39H2 (C-term) |
| Clonality | Polyclonal |
| Preparation | This SUV39H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 367-395 amino acids from the C-terminal region of human SUV39H2. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats. SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as cell cycle regulation, transcriptional repression and regulation of telomere length. May participate in regulation of higher order chromatin organization during spermatogenesis.
Specificity
Predicted Reactivity
Mouse, Monkey
Other Names
SUV39H2; KMT1B; Histone-lysine N-methyltransferase SUV39H2; Histone H3-K9 methyltransferase 2; Lysine N-methyltransferase 1B; Suppressor of variegation 3-9 homolog 2
NCBI Accession #
NP_001180353.1;NP_001180354.1;NP_001180355.1;NP_001180356.1;NP_078946.1
Other Accession #
Q9EQQ0; Q4R3E0; NP_078946.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
46682
Recommended Dilutions
WB: 1:1000
 | SUV39H2 Antibody (C-term) (Cat# 102-14145) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SUV39H2 antibody detected the SUV39H2 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.