Anti-SUZ12 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q15022
Gene Id	23512
Gene Symbols	SUZ12
Protein Name / Synonyms	SUZ12 (C-term)
Clonality	Polyclonal
Preparation	This SUZ12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 559-588 amino acids from the C-terminal region of human SUZ12.
Concentration (lot specific)	0.930 mg/ml
Recommended Applications	Western Blotting
Research Area	Cancer
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

Specificity

Predicted Reactivity

Mouse

Other Names

SUZ12;CHET9; JJAZ1; KIAA0160; Polycomb protein SUZ12; Polycomb protein SUZ12; Chromatin precipitated E2F target 9 protein; Polycomb protein SUZ12; Joined to JAZF1 protein; Polycomb protein SUZ12; Suppressor of zeste 12 protein homolog

NCBI Accession #

NP_056170.2

Other Accession #

Q80U70

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

83055

Recommended Dilutions

WB: 1:1000

SUZ12 Antibody (C-term) (Cat# 102-14680) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the SUZ12 antibody detected the SUZ12 protein (arrow).

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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