Anti-Tacrolimus (FK-506) Antibody

Catalog #: DS-MB-02738

Mouse Anti-Tacrolimus (FK-506)

Product Description

Specifications

Size	0.2 mg
Estimated Lead Time	1-2 weeks
Specificity	This product detects FK-506, a macrolide with similar but more potent immunosuppressant activity than cyclosporine. It is a 23-membered lactone produced by the bacteria Streptomyces tsukubaensis. FK-506 inhibits signal transduction and interleukin-2 transcription in CD4+ T helper lymphocytes, and is mainly used after allogenic organ transplantation to reduce organ rejection. Side effects of FK-506 treatment include nephrotoxicity, neurotoxicity, diabetes mellitus and hypertension.
Host Species	Mouse
Protein Name / Synonyms	Tacrolimus (FK-506)
Concentration (lot specific)	Ig concentration 1.0mg/ml
Recommended Applications	ELISA
Shipping Type	Blue ice
Storage	-20°C

Description

Storage/Stability

Store at +4 °C or at -20 °C if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
If stored in this manner, this product is stable for 18 months after receipt.

Format

Supplied as:

Purified IgM - liquid

Formulation:

TRIS buffered saline

Format Type:

Purified

Preparation

Immunogen:

FK-506-BSA conjugate

Preservative:

0.09%

Sodium Azide (NaN₃)

This product

Spleen cells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line.

Expiration:

12 months from the date of shipment when stored properly.

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