Anti-TAPBP (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O15533
Gene Id	6892
Gene Symbols	TAPBP
Protein Name / Synonyms	TAPBP (N-term)
Clonality	Polyclonal
Preparation	This TAPBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human TAPBP.
Concentration (lot specific)	0.350 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Specificity

Other Names

TAPBP; NGS17; TAPA; Tapasin; NGS-17; TAP-associated protein; TAP-binding protein

NCBI Accession #

NP_003181.3;NP_757345.2;NP_757346.2

Other Accession #

NP_003181.3

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

47626

Recommended Dilutions

WB: 1:1000

TAPBP Antibody (N-term) (Cat# 102-13971) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TAPBP antibody detected the TAPBP protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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