Anti-TBP Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Accession Number	P20226
Gene Id	6908
Gene Symbols	TBP
Protein Name / Synonyms	TBP
Clonality	Monoclonal
Preparation	Purified His-tagged TBP protein was used to produced this monoclonal antibody.
Concentration (lot specific)	0.370 mg/ml
Recommended Applications	IHC-P, Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

Specificity

Other Names

TBP;GTF2D1; TF2D; TFIID; TATA-box-binding protein; TATA-box-binding protein; TATA sequence-binding protein; TATA-box-binding protein; TATA-binding factor; TATA-box-binding protein; TATA-box factor; TATA-box-binding protein; Transcription initiation factor TFIID TBP subunit

NCBI Accession #

NP_001165556.1;NP_003185.1

Format

Type

Mouse Monoclonal Antibody (Mab)

Calculated Molecular Weight (Da)

37698

Recommended Dilutions

WB: 1:1000

TBP Antibody (Cat# 102-10412) western blot analysis in Hela,HepG2,mouse NIH/3T3 cell line lysates (35ug/lane).This demonstrates the TBP antibody detected the TBP protein (arrow).

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

Featured Products