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Anti-TCEB2 (Center) Antibody
Catalog #: 102-12430
Rabbit Anti-Human TCEB2 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q15370 |
| Gene Id | 6923 |
| Gene Symbols | TCEB2 |
| Protein Name / Synonyms | TCEB2 (Center) |
| Clonality | Polyclonal |
| Preparation | This TCEB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-48 amino acids from the Central region of human TCEB2. |
| Concentration (lot specific) | 0.400 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13.
Specificity
Other Names
TCEB2; Transcription elongation factor B polypeptide 2; Elongin 18 kDa subunit; Elongin-B; RNA polymerase II transcription factor SIII subunit B; SIII p18
NCBI Accession #
NP_009039.1;NP_996896.1
Other Accession #
NP_009039.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
13133
Recommended Dilutions
WB: 1:1000
 | TCEB2 Antibody (Center) (Cat# 102-12430) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the TCEB2 antibody detected the TCEB2 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.