Anti-THBD (C-term) Antibody

Product Description

Specifications

Size	200 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P07204\|Q71U07
Gene Id	7056
Gene Symbols	THBD
Protein Name / Synonyms	Thrombomodulin, TM, Fetomodulin, CD141, THBD, THRM
Clonality	Polyclonal
Clone	RB56904
Isotype	Kappa, Rabbit
Recommended Applications	FC, Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Other Information

Antigen Type

Synthesized Peptide

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

60329

Antigen Source

Human

Images

FC (1:25)

Overlay histogram showing A549 cells stained with 102-25239(green line). The cells were fixed with 2% paraformaldehyde (10 min) and then permeabilized with 90% methanol for 10 min. The cells were then icubated in 2% bovine serum albumin to block non-specific protein-protein interactions followed by the antibody (102-25239, 1:25 dilution) for 60 min at 37ºC. The secondary antibody used was Goat-Anti-Rabbit IgG, DyLight® 488 Conjugated Highly Cross-Adsorbed(1583138) at 1/200 dilution for 40 min at 37ºC. Isotype control antibody (blue line) was rabbit IgG1 (1?g/1x10

Expiration:

12 months from the date of shipment when stored properly.

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