Rabbit Anti-TLK2 (Center) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | Q86UE8 |
| Gene Id | 11011 |
| Gene Symbols | TLK2 |
| Protein Name / Synonyms | TLK2 (Center) |
| Clonality | Polyclonal |
| Preparation | This TLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-171 amino acids from the Central region of human TLK2. |
| Concentration (lot specific) | 1.780 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
TLK2, a member of the Ser/Thr protein kinase family, is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. The TLK2 enzyme is cell-cycle regulated, with maximal activity in S-phase. It is inactivated by phosphorylation at Ser-750, potentially by CHK1. TLK2 heterodimerizes with TLK1. This nuclear protein is widely expressed, with presence in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle tissues, and in several adult cell lines.
Specificity
Other Names
TLK2; Serine/threonine-protein kinase tousled-like 2; PKU-alpha; Tousled-like kinase 2
NCBI Accession #
NP_001106178.1;NP_006843.2
Other Accession #
Q9UKI7
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
87661
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of anti-TLK2 Antibody (Center) (Cat# 102-17800) in mouse testis tissue lysates (35ug/lane).TLK2(arrow) was detected using the purified Pab. |
 | TLK2 Antibody (K155) (Cat# 102-17800) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the TLK2 antibody detected the TLK2 protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.