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Anti-TLR9 (C-term) Antibody
Catalog #: 102-12119
Rabbit Anti-Human TLR9 (C-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9NR96 |
| Gene Id | 54106 |
| Gene Symbols | TLR9 |
| Protein Name / Synonyms | TLR9 (C-term) |
| Clonality | Polyclonal |
| Preparation | This TLR9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 842-870 amino acids from the C-terminal region of human TLR9. |
| Concentration (lot specific) | 0.7 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Research Area | Cancer, Inflammation, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
Specificity
Other Names
TLR9; Toll-like receptor 9; CD_antigen=CD289; Flags: Precursor
NCBI Accession #
NP_059138.1
Other Accession #
NP_059138.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
115860
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | TLR9 Antibody (C-term) (Cat# 102-12119) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the TLR9 antibody detected the TLR9 protein (arrow). |
 | TLR9 Antibody (C-term) (Cat# 102-12119) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.