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Anti-TMEM43 (Center) Antibody
Catalog #: 102-11660
Rabbit Anti-Human TMEM43 (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q9BTV4 |
| Gene Id | 79188 |
| Gene Symbols | TMEM43 |
| Protein Name / Synonyms | TMEM43 (Center) |
| Clonality | Polyclonal |
| Preparation | This TMEM43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human TMEM43. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Cardiovascular Disease |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
TMEM43; Transmembrane protein 43; Protein LUMA
NCBI Accession #
NP_077310.1
Other Accession #
Q5XIP9; Q9DBS1; NP_077310.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
44876
Recommended Dilutions
WB: 1:1000; IHC: 1:10-50
 | TMEM43 Antibody (Center) (Cat# 102-11660) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TMEM43 antibody detected the TMEM43 protein (arrow). |
 | TMEM43 Antibody (Center) (Cat# 102-11660)immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TMEM43 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.