Rabbit Anti-Human TNF (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P01375 |
| Gene Id | 7124 |
| Gene Symbols | TNF |
| Protein Name / Synonyms | TNF (C-term) |
| Clonality | Polyclonal |
| Preparation | This TNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the C-terminal region of human TNF. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, FC |
| Research Area | Cardiovascular Disease, Cancer, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.
Specificity
Other Names
TNF; TNFA; TNFSF2; Tumor necrosis factor; Cachectin; TNF-alpha; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; N-terminal fragment; Intracellular domain 1; Intracellular domain 2; C-domain 1; C-domain 2; Tumor necrosis factor, soluble form
NCBI Accession #
NP_000585.2
Other Accession #
NP_000585.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
25644
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | TNF Antibody (C-term) (Cat# 102-12041) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TNF antibody detected the TNF protein (arrow). |
 | TNF Antibody (C-term) (Cat# 102-12041) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.