Anti-Transglutaminase (TGM2) (Center T428) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P21980
Gene Id	7052
Gene Symbols	TGM2
Protein Name / Synonyms	Transglutaminase (TGM2) (Center T428)
Clonality	Polyclonal
Preparation	This Transglutaminase (TGM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-442 amino acids from the Central region of human Transglutaminase (TGM2).
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Research Area	Angiogenesis, Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. TGM2 acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. It has been identified as the autoantigen implicated in celiac disease.

Specificity

Other Names

TGM2; Protein-glutamine gamma-glutamyltransferase 2; Tissue transglutaminase; Transglutaminase C; Transglutaminase H; Transglutaminase-2

NCBI Accession #

NP_004604.2;NP_945189.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

77329

Recommended Dilutions

WB: 1:1000

Western blot analysis of TGM2 (arrow) using rabbit polyclonal TGM2 Antibody (Center T428) (Cat# 102-17644). 293 cell lysates (2 ug/lane) either nontransfected (c) or transiently transfected with the TGM2 gene (Lane 2) (Origene Technologies).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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