Rabbit Anti-Human TrkA-pY791 Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P04629 |
| Gene Id | 4914 |
| Gene Symbols | NTRK1 |
| Protein Name / Synonyms | TrkA-pY791 |
| Clonality | Polyclonal |
| Preparation | This TrkA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 769-796 amino acids from human TrkA. |
| Concentration (lot specific) | 0.260 mg/ml |
| Recommended Applications | FC, IHC-P, Western Blotting |
| Research Area | Angiogenesis, Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
TRKA (also known as NTRK1)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Specificity
Other Names
NTRK1; MTC; TRK; TRKA; High affinity nerve growth factor receptor; Neurotrophic tyrosine kinase receptor type 1; TRK1-transforming tyrosine kinase protein; Tropomyosin-related kinase A; Tyrosine kinase receptor; Tyrosine kinase receptor A; gp140trk; p140-TrkA
NCBI Accession #
NP_001007793.1;NP_001012331.1;NP_002520.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
87497
Recommended Dilutions
WB: 1:1000; FC: 1:10-50; IHC: 1:10-50
 | Western blot analysis of hTrkA-pY791 (Cat# 102-17558) in HepG2 cell line lysates (35ug/lane). TRK (arrow) was detected using the purified Pab. |
 | TrkA-pY791 Antibody (Cat# 102-17558) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
 | TrkA-pY791 Antibody (102-17558)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TrkA-pY791 Antibody for immunohistochemistry. Clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.