Rabbit Anti-Human TSC1 (Center T417) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q92574 |
| Gene Id | 7248 |
| Gene Symbols | TSC1 |
| Protein Name / Synonyms | TSC1 (Center T417) |
| Clonality | Polyclonal |
| Preparation | This TSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the Central region of human TSC1. |
| Concentration (lot specific) | 0.330 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cardiovascular Disease, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.
Specificity
Other Names
TSC1;KIAA0243; TSC; Hamartin; Hamartin; Tuberous sclerosis 1 protein
NCBI Accession #
NP_000359.1;NP_001155898.1;NP_001155899.1
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
129767
Recommended Dilutions
WB: 1:1000
 | TSC1 Antibody (Center T417) (Cat# 102-14662) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the TSC1 antibody detected the TSC1 protein (arrow). |
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.