RayBiotech

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Anti-TSC2 (N-term) Antibody

Catalog #: 102-14433

Rabbit Anti-Human TSC2 (N-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
P49815
Gene Id
7249
Gene Symbols
TSC2
Protein Name / Synonyms
TSC2 (N-term)
ClonalityPolyclonal
PreparationThis TSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 479-508 amino acids from the N-terminal region of human TSC2.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting
Research AreaCardiovascular Disease, Autophagy
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specificity

Predicted Reactivity
Mouse, Rat
Other Names
TSC2; TSC4; Tuberin; Tuberous sclerosis 2 protein
NCBI Accession #
NP_000539.2;NP_001070651.1;NP_001107854.1
Other Accession #
P49816; Q61037; NP_000539.2

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
200608
Recommended Dilutions
WB: 1:1000
TSC2 Antibody (N-term) (Cat# 102-14433) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TSC2 antibody detected the TSC2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.