Anti-TXN (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P10599
Gene Id	7295
Gene Symbols	TXN
Protein Name / Synonyms	TXN (C-term)
Clonality	Polyclonal
Preparation	This TXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the C-terminal region of human TXN.
Concentration (lot specific)	0.400 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).

Specificity

Predicted Reactivity

Mouse, Rat, Bovine, Pig, Rabbit

Other Names

TXN;TRDX; TRX; TRX1; Thioredoxin; Thioredoxin; ATL-derived factor; Thioredoxin; Surface-associated sulphydryl protein

NCBI Accession #

NP_001231867.1;NP_003320.2

Other Accession #

P11232; P08628; P82460; P10639; O97680

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

11737

Recommended Dilutions

WB: 1:1000

TXN Antibody (C-term) (Cat# 102-14693) western blot analysis in A549,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the TXN antibody detected the TXN protein (arrow).

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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