Anti-Tyrosyl tRNA synthetase (YARS) (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P54577
Gene Id	8565
Gene Symbols	YARS
Protein Name / Synonyms	Tyrosyl tRNA synthetase (YARS) (N-term)
Clonality	Polyclonal
Preparation	This Tyrosyl tRNA synthetase (YARS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-190 amino acids from the N-terminal region of human Tyrosyl tRNA synthetase (YARS).
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.

Specificity

Predicted Reactivity

Rat

Other Names

YARS; Tyrosine--tRNA ligase, cytoplasmic; Tyrosyl-tRNA synthetase

NCBI Accession #

NP_003671.1

Other Accession #

Q4KM49

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

59143

Recommended Dilutions

WB: 1:1000

Western blot analysis of anti-YARS Pab (Cat# 102-17429) in Jurkat cell line lysates (35ug/lane).YARS (arrow) was detected using the purified Pab.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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