Anti-UBE2D3 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P61077
Gene Id	7323
Gene Symbols	UBE2D3
Protein Name / Synonyms	UBE2D3 (C-term)
Clonality	Polyclonal
Preparation	This UBE2D3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-136 amino acids from the C-terminal region of human UBE2D3.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.

Specificity

Predicted Reactivity

Mouse, Rat, Bovine, Pig, Monkey

Other Names

UBE2D3; UBC5C; UBCH5C; Ubiquitin-conjugating enzyme E2 D3; Ubiquitin carrier protein D3; Ubiquitin-conjugating enzyme E2(17)KB 3; Ubiquitin-conjugating enzyme E2-17 kDa 3; Ubiquitin-protein ligase D3

NCBI Accession #

NP_003331.1;NP_871615.1;NP_871616.1;NP_871617.1;NP_871618.1;NP_871619.1;NP_871620.1;NP_871621.1;NP_871622.1

Other Accession #

P61078; P61079; Q4R5N4; Q3ZCF7; Q06AA9; NP_003331.1; NP_871615.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

16687

Recommended Dilutions

WB: 1:1000

	UBE2D3 Antibody (C-term) (Cat# 102-13145) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the UBE2D3 antibody detected the UBE2D3 protein (arrow).
	Western blot analysis of UBE2D3 (arrow) using rabbit polyclonal UBE2D3 Antibody (C-term) (Cat# 102-13145). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the UBE2D3 gene.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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