RayBiotech

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ISO 13485:2016 cGMP

Anti-UBE2K Antibody

Catalog #: 144-61995

UBE2K pAb

Product Description

Specifications

Size20 µL, 100 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
P61086
Gene Id
3093
Gene Symbols
UBE2K
Protein Name / Synonyms
UBE2K, E2-25K, HIP2, HYPG, LIG, UBC1, ubiquitin-conjugating enzyme E2 K
IsotypeIgG
Purity
Affinity purification
BuffersPBS with 0.02% sodium azide, 50% glycerol, pH7.3
Recommended ApplicationsWestern Blotting
Research AreaCancer
Shipping TypeBlue ice
Storage-20°C

Description

Background

The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

Dilutions

WB 1:500 - 1:2000

Format

Calculated MW
16kDa/17kDa/22kDa
Observed MW
22kDa

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE2K (NP_005330.1).

Modification

Unmodified

Storage

Store at -20°. Avoid freeze / thaw cycles.

Images

Western blot

Expiration:
12 months from the date of shipment when stored properly.