Anti-UBE2L6 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O14933
Gene Id	9246
Gene Symbols	UBE2L6
Protein Name / Synonyms	UBE2L6 (C-term)
Clonality	Polyclonal
Preparation	This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-153 amino acids from the C-terminal region of human UBE2L6.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.

Specificity

Other Names

UBE2L6; UBCH8; Ubiquitin/ISG15-conjugating enzyme E2 L6; Retinoic acid-induced gene B protein; UbcH8; Ubiquitin carrier protein L6; Ubiquitin-protein ligase L6

NCBI Accession #

NP_004214.1;NP_937826.1

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

17769

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50

	The UBE2L6 Antibody (C-term) (Cat# 102-14974) is used in Western blot to detect UBE2L6 in HL-60 cell lysate.
	Formalin-fixed and paraffin-embedded breast carcinoma tissue reacted with UBE2L6 Antibody (C-term)(Cat# 102-14974), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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