Rabbit Anti-Human UBE2L6 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O14933 |
| Gene Id | 9246 |
| Gene Symbols | UBE2L6 |
| Protein Name / Synonyms | UBE2L6 (N-term) |
| Clonality | Polyclonal |
| Preparation | This UBE2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human UBE2L6. |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L6 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to function in the E6/E6-ap-induced ubiquitination of p53.
Specificity
Other Names
UBE2L6; UBCH8; Ubiquitin/ISG15-conjugating enzyme E2 L6; Retinoic acid-induced gene B protein; UbcH8; Ubiquitin carrier protein L6; Ubiquitin-protein ligase L6
NCBI Accession #
NP_004214.1;NP_937826.1
Other Accession #
NP_937826
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
17769
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of lysate from HL-60 cell line, using UBE2L6 Antibody (M1) (Cat# 102-14973). 102-14973 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug. |
 | Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with UBE2L6 Antibody (N-term)(Cat# 102-14973), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.