Anti-UCK (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human, Mouse
Host Species	Rabbit
Accession Number	P30085
Gene Id	51727
Gene Symbols	CMPK1
Protein Name / Synonyms	UCK (N-term)
Clonality	Polyclonal
Preparation	This UCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-48 amino acids from the N-terminal region of human UCK.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

UCK1 (Uridine-cytidine kinase 1) phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate. This enzyme does not phosphorylate deoxyribonucleosides or purine ribonucleosides. Of note, UCK1 is able to use either ATP or GTP as a phosphate donor. UCK1 also possesses the ability to phosphorylate a number of cytidine and uridine nucleoside analogs such as 6-azauridine, 5-fluorouridine, 4-thiouridine, 5-bromouridine, N(4)-acetylcytidine, N(4)-benzoylcytidine, 5-fluorocytidine, 2-thiocytidine, 5-methylcytidine, and N(4)-anisoylcytidine.

Specificity

Predicted Reactivity

Rat, Bovine, Pig

Other Names

CMPK1; CMK; CMPK; UCK; UMK; UMPK; UMP-CMP kinase; Cytidine monophosphate kinase; Cytidylate kinase; Deoxycytidylate kinase; Uridine monophosphate kinase; Uridine monophosphate/cytidine monophosphate kinase

NCBI Accession #

NP_001129612.1;NP_057392.1

Other Accession #

Q4KM73; Q29561; Q9DBP5; Q2KIW9

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

22222

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	The anti-UCK Pab (Cat# 102-17813) is used in Western blot to detect UCK in mouse cerebellum tissue lysate (Lane 1) and HepG2 cell lysate (Lane 2).
	Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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