Anti-UNC13B (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	O14795
Gene Id	10497
Gene Symbols	UNC13B
Protein Name / Synonyms	UNC13B (Center)
Clonality	Polyclonal
Preparation	This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1062-1091 amino acids from the Central region of human UNC13B.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting, FC
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).

Specificity

Predicted Reactivity

Mouse

Other Names

UNC13B; UNC13; Protein unc-13 homolog B; Munc13-2

NCBI Accession #

NP_006368.3

Other Accession #

Q9Z1N9

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

180679

Recommended Dilutions

WB: 1:1000; FC: 1:10-50

	Western blot analysis of UNC13B Antibody (Center) (Cat# 102-18070) in 293 cell line lysates (35ug/lane). UNC13B (arrow) was detected using the purified Pab.
	UNC13B Antibody (Center) (Cat# 102-18070) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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