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Anti-UNC5C (Center) Antibody
Catalog #: 102-17015
Rabbit Anti-Human UNC5C (Center) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O95185 |
| Gene Id | 8633 |
| Gene Symbols | UNC5C |
| Protein Name / Synonyms | UNC5C (Center) |
| Clonality | Polyclonal |
| Preparation | This UNC5C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 188-217 amino acids from the Central region of human UNC5C. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
UNC5C belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.
Specificity
Predicted Reactivity
Rat
Other Names
UNC5C; UNC5H3; Netrin receptor UNC5C; Protein unc-5 homolog 3; Protein unc-5 homolog C
NCBI Accession #
NP_003719.3
Other Accession #
Q761X5
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
103146
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | Western blot analysis of UNC5C Antibody (Center) (Cat# 102-17015) in K562 cell line lysates (35ug/lane). UNC5C (arrow) was detected using the purified Pab. |
 | Formalin-fixed and paraffin-embedded human brain tissue with UNC5C Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
 | Flow cytometric analysis of K562 cells using UNC5C Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.