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Anti-VE Cadherin (CDH5) (N-term) Antibody
Catalog #: 102-15095
Rabbit Anti-Human VE Cadherin (CDH5) (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P33151 |
| Gene Id | 1003 |
| Gene Symbols | CDH5 |
| Protein Name / Synonyms | VE Cadherin (CDH5) (N-term) |
| Clonality | Polyclonal |
| Preparation | This VE Cadherin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-134 amino acids from the N-terminal region of human VE Cadherin. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | FC, Western Blotting |
| Research Area | Angiogenesis, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
CDH5 is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions.
Specificity
Other Names
CDH5; Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; CD_antigen=CD144; Flags: Precursor
NCBI Accession #
NP_001786.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
87528
Recommended Dilutions
WB: 1:1000; FC: 1:10-50
 | Western blot analysis of anti-CDH5 Pab (Cat# 102-15095) in 293 cell line lysates (35ug/lane). CDH5(arrow) was detected using the purified Pab. |
 | Flow cytometric analysis of 293 cells using VE Cadherin Antibody (CDH5) (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.