Anti-VEGF1 (N-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P15692
Gene Id	7422
Gene Symbols	VEGFA
Protein Name / Synonyms	VEGF1 (N-term)
Clonality	Polyclonal
Preparation	This VEGF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-95 amino acids from the N-terminal region of human VEGF1.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting
Research Area	Angiogenesis, Cardiovascular Disease, Vascular Biology
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

VEGF1 is a member of the PDGF/VEGF growth factor family and and is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein are linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in VEGF1 have been associated with proliferative and nonproliferative diabetic retinopathy.

Specificity

Other Names

VEGFA; VEGF; Vascular endothelial growth factor A; Vascular permeability factor

NCBI Accession #

NP_001020537.2;NP_001020538.2;NP_001020539.2;NP_001020540.2;NP_001020541.2;NP_001028928.1;NP_001165093.1;NP_001165094.1;NP_001165095.1;NP_001165096.1;NP_001165097.1;NP_001165098.1;NP_001165099.1;NP_00

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

27042

Recommended Dilutions

WB: 1:1000

Western blot analysis of VEGF1 Antibody (N-term) polyclonal antibody(Cat# 102-16729)(arrow). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the VEGF1 gene (Lane 2) (Origene Technologies). Molecular weight of monomeric VEGF1 is 27042 Da; higher observed molecular weight band is consistent with common form of disulfide linked homodimer.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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