Anti-VEGFA (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P15692
Gene Id	7422
Gene Symbols	VEGFA
Protein Name / Synonyms	VEGFA (Center)
Clonality	Polyclonal
Preparation	This VEGFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the Central region of human VEGFA.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Research Area	Angiogenesis, Cardiovascular Disease, Vascular Biology
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.

Specificity

Other Names

VEGFA; VEGF; Vascular endothelial growth factor A; Vascular permeability factor

NCBI Accession #

NP_001020537.2;NP_001020538.2;NP_001020539.2;NP_001020540.2;NP_001020541.2;NP_001028928.1;NP_001165093.1;NP_001165094.1;NP_001165095.1;NP_001165096.1;NP_001165097.1;NP_001165098.1;NP_001165099.1;NP_00

Other Accession #

NP_001020537.2; NP_001020538.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

27042

Recommended Dilutions

WB: 1:1000

VEGFA Antibody (Center) (Cat# 102-11432) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the VEGFA antibody detected the VEGFA protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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