Anti-VGFR2 Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	P35968
Gene Id	3791
Gene Symbols	KDR
Protein Name / Synonyms	VGFR2
Clonality	Polyclonal
Preparation	This VGFR2 antibody is generated from rabbits immunized with a His fusion protein from human VGFR2.
Concentration (lot specific)	2.0 mg/ml
Recommended Applications	Western Blotting, IHC-P
Research Area	Angiogenesis, Cancer, Autophagy
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

VEGF is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc..

Specificity

Other Names

KDR; FLK1; VEGFR2; Vascular endothelial growth factor receptor 2; Fetal liver kinase 1; Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1; CD_antigen=CD309; Flags: Precursor

NCBI Accession #

NP_002244.1

Other Accession #

NP_002244

Format

Type

Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

151527

Recommended Dilutions

WB: 1:1000; IHC: 1:50-100

	Western blot analysis of VGFR2 Antibody (Cat# 102-18127) in mouse cerebellum tissue lysates (35ug/lane). VGFR2 (arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human breast carcinoma reacted with VGFR2 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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