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Anti-Vitronectin (V3) Antibody, Biotinylated
Catalog #: 130-00001B-50
Rabbit anti-Vitronectin (V3) Biotinylated Antibody, 50 ug
Product Description
Specifications
| Size | 50 µg |
| Estimated Lead Time | 1-2 business days |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P04004 |
| Gene Id | 7448 |
| Gene Symbols | VTN |
| Clonality | Polyclonal |
| Immunogen | The immunogen was a synthetic peptide (VTN). This antibody was produced from a rabbit immunized with this peptide conjugated with KLH. The IgG fraction was purified from rabbit serum by Protein G affinity chromatograpy. |
| Isotype | IgG |
| Recommended Applications | ELISA (recommended work dilution= 1: 32, 000) |
| Reconstitution | A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e.g. sodium azide). The final amount is indicated on the shipping vial. |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Description
Vitronectin also known as VTN is a protein that in humans is encoded by the VTN gene. The protein encoded by this gene is a member of the pexin family. Vitronectin is an abundant glycoprotein found in serum and the extracellular matrix and promotes cell adhesion and spreading, inhibits the membranedamaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Vitronectin has been speculated to be involved in hemostasis and tumor malignancy.
Storage / Stability
The antibody is stable for at least 1 year from the date of receipt when stored at -20°C to -70°C. Reconstituted antibody can also be aliquotted and stored at 4°C for 1 month or at -20°C to -70°C in a manual defrost freezer for many months without detectable loss activity. Please avoid freeze-thaw cycles.
Specificity
This antibody can specifically bind to human VTN. The cross reactivity with mouse and rat VTN was detected
References
- Preissner KT, Seiffert D (January 1998). "Role of vitronectin and its receptors in haemostasis and vascular remodeling". Thromb. Res. 89 (1): 121.
- Felding-Habermann B, Cheresh DA (October 1993). "Vitronectin and its receptors". Curr. Opin. Cell Biol. 5 (5): 8648.
Expiration:
12 months from the date of shipment when stored properly.