Rabbit Anti-Human VPS4B (C-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O75351 |
| Gene Id | 9525 |
| Gene Symbols | VPS4B |
| Protein Name / Synonyms | VPS4B (C-term) |
| Clonality | Polyclonal |
| Preparation | This VPS4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-332 amino acids from the C-terminal region of human VPS4B. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Angiogenesis, Autophagy |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq].
Specificity
Other Names
VPS4B; SKD1; VPS42; Vacuolar protein sorting-associated protein 4B; Cell migration-inducing gene 1 protein; Suppressor of K(+) transport growth defect 1
NCBI Accession #
NP_004860.2
Other Accession #
NP_004860.2
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
49302
Recommended Dilutions
WB: 1:1000
 | VPS4B Antibody (C-term) (Cat# 102-12177) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the VPS4B antibody detected the VPS4B protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.