Anti-WFDC1 (C-term H163) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q9HC57
Gene Id	58189
Gene Symbols	WFDC1
Protein Name / Synonyms	WFDC1 (C-term H163)
Clonality	Polyclonal
Preparation	This WFDC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-177 amino acids from the C-terminal region of human WFDC1.
Concentration (lot specific)	0.300 mg/ml
Recommended Applications	Western Blotting, IHC-P, FC
Research Area	Inflammation
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

This gene encodes a member of the WAP-type four disulfide core domain family. The WAP-type four-disulfide core domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. The encoded protein shares 81% amino acid identity with the rat ps20 protein, which was originally identified as a secreted growth inhibitor. This gene is mapped to chromosome 16q24, an area of frequent loss of heterozygosity in cancers, including prostate, breast and hepatocellular cancers and Wilms' tumor. Owing to its location and a possible growth inhibitory property of its gene product, this gene is suggested to be a tumor suppressor gene.

Specificity

Other Names

WFDC1; PS20; WAP four-disulfide core domain protein 1; Prostate stromal protein ps20; ps20 growth inhibitor

NCBI Accession #

NP_067020.2

Other Accession #

NP_067020.2

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

23977

Recommended Dilutions

WB: 1:1000; IHC: 1:10-50; FC: 1:10-50

	WFDC1 Antibody (C-term H163) (Cat# 102-11585) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the WFDC1 antibody detected the WFDC1 protein (arrow).
	WFDC1 Antibody (C-term H163) (Cat# 102-11585)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of WFDC1 Antibody (C-term H163) for immunohistochemistry. Clinical relevance has not been evaluated.
	WFDC1 Antibody (C-term H163) (Cat# 102-11585) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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