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Anti-XIAP (BIRC4) (N-term) Antibody
Catalog #: 102-16649
Rabbit Anti-XIAP (BIRC4) (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Mouse |
| Host Species | Rabbit |
| Accession Number | P98170 |
| Gene Id | 331 |
| Gene Symbols | XIAP |
| Protein Name / Synonyms | XIAP (BIRC4) (N-term) |
| Clonality | Polyclonal |
| Preparation | This XIAP (BIRC4) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human XIAP (BIRC4). |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting, IHC-P |
| Research Area | Apoptosis, Cancer, Inflammation |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
BIRC4 is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, BIRC4 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. BIRC4 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.
Specificity
Other Names
XIAP; API3; BIRC4; IAP3; E3 ubiquitin-protein ligase XIAP; Baculoviral IAP repeat-containing protein 4; IAP-like protein; Inhibitor of apoptosis protein 3; X-linked inhibitor of apoptosis protein
NCBI Accession #
NP_001158.2;NP_001191330.1
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
56685
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100
 | Western blot analysis of anti-BIRC4 Antibody (N-term) (Cat# 102-16649) in Ramos cell line lysates (35ug/lane). BIRC4(arrow) was detected using the purified Pab. |
 | The anti-BIRC4 (N-term) Pab (Cat# 102-16649) is used in Western blot to detect BIRC4 in mouse liver tissue lysate. |
 | Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with BIRC4 antibody (N-term) (Cat# 102-16649), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.