3607 Parkway Ln Ste 200 Norcross, Georgia 30092
www.RayBiotech.com | info@raybiotech.com
770-729-2992 | +1-888-494-8555
ISO 13485:2016 cGMP
Anti-XPC (N-term) Antibody
Catalog #: 102-14393
Rabbit Anti-Human XPC(N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | Q01831 |
| Gene Id | 7508 |
| Gene Symbols | XPC |
| Protein Name / Synonyms | XPC(N-term) |
| Clonality | Polyclonal |
| Preparation | This XPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human XPC. |
| Concentration (lot specific) | 0.380 mg/ml |
| Recommended Applications | Western Blotting |
| Research Area | Cancer |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
Specificity
Other Names
XPC; XPCC; DNA repair protein complementing XP-C cells; Xeroderma pigmentosum group C-complementing protein; p125
NCBI Accession #
NP_001139241.1;NP_004619.3
Other Accession #
NP_001139241.1; NP_004619.3
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
105953
Recommended Dilutions
WB: 1:1000
 | XPC Antibody (N-term) (Cat# 102-14393) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the XPC antibody detected the XPC protein (arrow). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.