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Anti-XPO1 (C-term) Antibody
Catalog #: 102-27072
Rabbit Anti-XPO1 (C-term) Antibody, 400 µl
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | O14980|Q80U96|Q6P5F9 |
| Gene Id | 7514 |
| Gene Symbols | XPO1 |
| Protein Name / Synonyms | Exportin-1, Exp1, Chromosome region maintenance 1 protein homolog, XPO1, CRM1 |
| Clonality | Polyclonal |
| Clone | RB19972 |
| Isotype | Kappa, Rabbit |
| Recommended Applications | IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.
Other Information
NCBI Accession #
NP_003391.1
Antigen Type
Synthetic Peptide
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Calculated Molecular Weight (Da)
123386
Antigen Source
Human
Images
IHC-P (1:50~100)
Formalin-fixed and paraffin-embedded human brain tissue reacted with XPO1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.