Anti-XRCC4 (Center) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Human
Host Species	Rabbit
Accession Number	Q13426
Gene Id	7518
Gene Symbols	XRCC4
Protein Name / Synonyms	XRCC4 (Center)
Clonality	Polyclonal
Preparation	This XRCC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-234 amino acids from the Central region of human XRCC4.
Concentration (lot specific)	0.5 mg/ml
Recommended Applications	Western Blotting
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

The protein encoded by this gene functions together with DNA ligase IV and the DNA-dependent protein kinase in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. The non-homologous end-joining pathway is required both for normal development and for suppression of tumors. This gene functionally complements XR-1 Chinese hamster ovary cell mutant, which is impaired in DNA double-strand breaks produced by ionizing radiation and restriction enzymes. Alternative transcription initiation and alternative splicing generates several transcript variants. [provided by RefSeq].

Specificity

Other Names

XRCC4; DNA repair protein XRCC4; X-ray repair cross-complementing protein 4

NCBI Accession #

NP_003392.1;NP_071801.1;NP_072044.1

Other Accession #

NP_003392.1

Format

Type

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Calculated Molecular Weight (Da)

38287

Recommended Dilutions

WB: 1:1000

XRCC4 Antibody (Center)(Cat# 102-14047) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the XRCC4 antibody detected the XRCC4 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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