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Anti-YB1 (YBX1) (N-term) Antibody
Catalog #: 102-16734
Rabbit Anti-Human YB1 (YBX1) (N-term) Antibody, 400 ul
Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human |
| Host Species | Rabbit |
| Accession Number | P67809 |
| Gene Id | 4904 |
| Gene Symbols | YBX1 |
| Protein Name / Synonyms | YB1 (YBX1) (N-term) |
| Clonality | Polyclonal |
| Preparation | This YB1 (YBX1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the N-terminal region of human YB1 (YBX1). |
| Concentration (lot specific) | 2.0 mg/ml |
| Recommended Applications | Western Blotting |
| Shipping Type | Blue ice |
| Storage | -20°C |
Description
Introduction
YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.
Specificity
Predicted Reactivity
Mouse, Rat, Bovine, Chicken, Rabbit, Xenopus
Other Names
YBX1; NSEP1; YB1; Nuclease-sensitive element-binding protein 1; CCAAT-binding transcription factor I subunit A; DNA-binding protein B; Enhancer factor I subunit A; Y-box transcription factor; Y-box-binding protein 1
NCBI Accession #
NP_004550.2
Other Accession #
P21574; Q62764; Q9JKB3; P16989; Q9Z2C8; Q9Y2T7; P21573; P62961; Q28618; P62960; Q06066; P67808; Q00436
Format
Type
Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
35924
Recommended Dilutions
WB: 1:1000
 | Western blot analysis of anti-YBX1 Antibody (N-term) (Cat# 102-16734) in NCI-H460 cell line lysates (35ug/lane).YBX1(arrow) was detected using the purified Pab. |
 | Western blot analysis of YBX1 (arrow) using rabbit polyclonal YBX1 Antibody (N-term) (RB14116).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the YBX1 gene (Lane 2) (Origene Technologies). |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.