Rabbit Anti-YMEL1 (N-term) Antibody, 400 ul
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Product Description
Specifications
| Size | 400 µL |
| Estimated Lead Time | 1-2 weeks |
| Species | Human, Hamster |
| Host Species | Rabbit |
| Accession Number | Q96TA2 |
| Gene Id | 10730 |
| Gene Symbols | YME1L1 |
| Protein Name / Synonyms | YMEL1 (N-term) |
| Clonality | Polyclonal |
| Preparation | This YMEL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-219 amino acids from the N-terminal region of human YMEL1. |
| Concentration (lot specific) | 0.5 mg/ml |
| Recommended Applications | Western Blotting, IHC-P, FC |
| Shipping Type | Blue ice |
| Storage | -20°C |
Introduction
YMEL1 is the human ortholog of yeast mitochondrial AAA metalloprotease, Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies.
Specificity
Predicted Reactivity
Mouse, Rat
Other Names
YME1L1; FTSH1; YME1L; ATP-dependent zinc metalloprotease YME1L1; ATP-dependent metalloprotease FtsH1; Meg-4; Presenilin-associated metalloprotease; YME1-like protein 1
NCBI Accession #
NP_001240795.1;NP_055078.1;NP_647473.1
Other Accession #
Q925S8; O88967
Format
Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
86455
Recommended Dilutions
WB: 1:1000; IHC: 1:50-100; FC: 1:10-50
 | Western blot analysis of YMEL1 Antibody (N-term) (Cat# 102-15784) in HepG2 cell line lysates (35ug/lane). YMEL1 (arrow) was detected using the purified Pab. |
 | Western blot analysis of YMEL1 Antibody (N-term) (Cat# 102-15784) in CHO cell line lysates (35ug/lane). YMEL1 (arrow) was detected using the purified Pab. |
 | YMEL1 Antibody (N-term) (Cat# 102-15784) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the YMEL1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
 | YMEL1 Antibody (N-term) (Cat# 102-15784) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
Antigen Source
HUMAN
Storage/Stability
2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.