RayBiotech

3607 Parkway Ln Ste 200 Norcross, Georgia 30092

www.RayBiotech.com | info@raybiotech.com

770-729-2992 | +1-888-494-8555

ISO 13485:2016 cGMP

Anti-YTHD2 (C-term) Antibody

Catalog #: 102-12966

Rabbit Anti-Human YTHD2 (C-term) Antibody, 400 ul

Product Description

Specifications

Size400 µL
Estimated Lead Time1-2 weeks
SpeciesHuman
Host SpeciesRabbit
Accession Number
Q9Y5A9
Gene Id
51441
Gene Symbols
YTHDF2
Protein Name / Synonyms
YTHD2 (C-term)
ClonalityPolyclonal
PreparationThis YTHD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the C-terminal region of human YTHD2.
Concentration (lot specific)
0.5 mg/ml
Recommended ApplicationsWestern Blotting
Shipping TypeBlue ice
Storage-20°C

Description

Introduction

YTHDF2 is a member of the YTH (YT521-B homology) superfamily containing YTH domain. The YTH domain is typical for the eukaryotes and is particularly abundant in plants. The YTH domain is usually located in the middle of the protein sequence and may function in binding to RNA. In addition to a YTH domain, this protein has a proline rich region which may be involved in signal transduction. An Alu-rich domain has been identified in one of the introns of this gene, which is thought to be associated with human longevity. In addition, reciprocal translocations between this gene and the Runx1 (AML1) gene on chromosme 21 has been observed in patients with acute myeloid leukemia. This gene was initially mapped to chromosome 14, which was later turned out to be a pseudogene.

Specificity

Predicted Reactivity
Mouse, Bovine, Monkey
Other Names
YTHDF2; HGRG8; YTH domain family protein 2; CLL-associated antigen KW-14; High-glucose-regulated protein 8; Renal carcinoma antigen NY-REN-2
NCBI Accession #
NP_001166299.1;NP_001166599.1;NP_057342.2
Other Accession #
Q91YT7; Q4R5D9; Q0VCZ3; NP_001166299.1; NP_001166599.1

Format

Type
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Calculated Molecular Weight (Da)
62334
Recommended Dilutions
WB: 1:1000
YTHD2 Antibody (C-term) (Cat# 102-12966) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the YTHD2 antibody detected the YTHD2 protein (arrow).

Antigen Source

HUMAN

Storage/Stability

2-8°C (short-term); -20°C (long-term)
Expiration:
12 months from the date of shipment when stored properly.