Anti-Zebrafish mapk12 (C-term) Antibody

Product Description

Specifications

Size	400 µL
Estimated Lead Time	1-2 weeks
Species	Zebrafish
Host Species	Rabbit
Accession Number	O42376
Gene Symbols	mapk12
Protein Name / Synonyms	Mitogen-activated protein kinase 12, MAP kinase 12, MAPK 12, Stress-activated protein kinase 3, mapk12, sapk3
Clonality	Polyclonal
Clone	RB47232
Isotype	IgG
Recommended Applications	Western Blotting
Research Area	Neuroscience
Shipping Type	Blue ice
Storage	-20°C

Description

Introduction

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK12 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases such as MAPKAPK2, which are activated through phosphorylation and further phosphorylate additional targets (By similarity).

Other Information

Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Calculated Molecular Weight (Da)

41971

Antigen Source

DANRE

Images

WB (1:1000)

Western blot analysis of lysates from zebra fish brain, Zebrafish tissue lysate (from left to right), using (DANRE) mapk12 Antibody (C-term)(Cat. #102-27873). 102-27873 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane.

Storage/Stability

2-8°C (short-term); -20°C (long-term)

Expiration:

12 months from the date of shipment when stored properly.

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