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ISO 13485:2016 cGMP
CLOSTRIDIUM DIFFICILE TOXOID B
Catalog #: 229-20074
Product Description
Specifications
| Size | 50 µg |
| Estimated Lead Time | 1-2 weeks |
| Species | Bacteria |
| Purity | >95% by SDS-PAGE |
| Format | Inactivated toxoid derived from purified Clostridium difficile Toxin B - lyophilized |
| Formulation | 0.05M HEPES, 0.15M NaCl, 5% Sucrose |
| Concentration (lot specific) | ~0.2mg/ml after reconstitution |
| Preservative | None present |
| Recommended Applications | ELISA |
| Shipping Type | Ambient temperature |
| Storage | -20°C |
Description
Introduction
Clostridium difficile is a Gram-positive bacteria naturally present in the gut of some children and very few adults. Occasionally, the use of antibiotics to treat other infections may lead to C. difficile infection and severe diarrhoea and fever. Symptoms are caused by toxin A (an enterotoxin) and toxin B (a cytotoxin).
129-20074 is a highly purified, non toxic preparation derived from Clostridium difficile Toxin B. Antigenicity of this preparation is maintained to be no less than 90% of original toxin strength as measured by direct ELISA.
For a preparation of Toxoid A, see 129-20073.
129-20074 is a highly purified, non toxic preparation derived from Clostridium difficile Toxin B. Antigenicity of this preparation is maintained to be no less than 90% of original toxin strength as measured by direct ELISA.
For a preparation of Toxoid A, see 129-20073.
Inactivated using formaldehyde. No cell rounding in the sensitive verocytotoxicity assay at 2µg/ml compared to active toxin lethal dose of 4pg/ml.
Specifications
Size
50 ug
Stability & Storage
Storage/Stability
Prior to reconstitution store at +4°C.
After reconstitution store at +4°C or at -20°C for long-term storage.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. This protein may be stored for1 month from date of reconstitution if stored at +4°C.
After reconstitution store at +4°C or at -20°C for long-term storage.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. This protein may be stored for1 month from date of reconstitution if stored at +4°C.